I have read a couple of books by Amor Towles and thoroughly enjoyed them so I was eager to read this novel. I am not a keen reader of books set in the USA but occasionally I will find a book that makes me rethink my prejudice on that front. This is one that certainly made me realise that I should lose my bias against American novels.
There is a wonderful review in the Guardian which is well worth a read.
The novel is set in 1950s America and follows the adventures of two brothers and the highway across America.
“In June, 1954, eighteen-year-old Emmett Watson is driven home to Nebraska by the warden of the work farm where he has just served a year for involuntary manslaughter. His mother long gone, his father recently deceased, and the family farm foreclosed upon by the bank, Emmett’s intention is to pick up his eight-year-old brother and head west where they can start their lives anew. But when the warden drives away, Emmett discovers that two friends from the work farm have hidden themselves in the trunk of the warden’s car. Together, they have hatched an altogether different plan for Emmett’s future.”
I enjoyed the many interesting characters in this novel and a completely different theme to Towles two previous books.
Gippsland Granny 
I just bought this as an audiobook and now I’m anxious to read it! So glad I saw your post. Also, the Lincoln Highway goes through Denver, so of course need to read it. 🙂